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Diloxanide furoate is a relative of chloramphenicol used since the 1950s.

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PREGNANCYThere are no adequate studies done on chloramphenicol to determine safe and effective use in pregnant women.

Wash your hands before you use the dropsRemove the cap from the bottleor the tip of the unit if you are using a single-use unitTilt your head back a little and pull the lower lid of your eye downwards to form a pocketHold the bottleor single-use unitupside down near to your eyeTry not to touch your eye as you do thisApply enough pressure to release one drop into your eyeOnly use a second drop if the first drop missed going into your eyeClose your eye for a minute or twoand press gently on the side of your nose where the corner of your eye meets your noseThis helps to stop the drop from draining away and keeps it in your eyeRepeat the process in your other eye if both eyes are affectedReplace the capor if you are using a single-use unitthrow the used unit away

Chloramphenicol injection may cause a condition called gray syndrome in premature and newborn infantsThere have also been reports of gray syndrome in children up to age 2 and in newborns whose mothers were treated with chloramphenicol injection during laborSymptomswhich usually occur after 3 to 4 days of treatmentmay includestomach bloatingvomitingblue lips and skin due to lack of oxygen in the bloodlow blood pressuredifficulty breathingand deathIf treatment is stopped at the first sign of any symptomsthe symptoms may go awayand the infant may recover completelyTalk to your doctor about the risks of using this medication during labor or to treat babies and young children.

Chloramphenicol exerts its antibacterial effect by binding to bacterial ribosomes and inhibiting bacterial protein synthesis at an early stage.

Chloramphenicol may cause Gray syndrome and seriousfatal blood dyscrasiasGray syndrome occurs in pre-mature infants and neonatesIt involves abdominal distentionpallid cyanosisand vasomotor collapse leading to deathBlood dyscrasias are reductions in blood cells leading to aplastic anemiathrombocytopeniaand granulocytopenia.

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